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Home > PRODUCTS > Gas Control > Animal Hypoxic and Hyperoxic Experiments

Laboratory Animal Hyperbaric Chamber

Product model:

ProOx-820

Detailed introduction:

Animal experiment hyperbaric oxygen chamber is specially designed for experimental animals, which can be used to produce hyperbaric oxygen equipment. It has manual and automatic operation modes and can be used for the study of various hypoxia symptoms.... View details >
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Detailed Introduction

Animal experiment hyperbaric oxygen chamber is specially designed for experimental animals, which can be used to produce hyperbaric oxygen equipment. It has manual and automatic operation modes and can be used for the study of various hypoxia symptoms.

Product Features

· Working Pressure 0-0.3MPa

· Safety therapeutic pressure can be set. Solenoid valve will be automatically triggered when pressure exceeds the set limit and excessive pressure will be released.

· Built-in mechanical safety valve.The pressure is automatically released when it exceeds the limit, to provide double protection. 

· CO2 monitoring and alarm function will be triggered in case of abnormal ventilation in the chamber or CO2 retention, ensuring the safety of animals. 

·  The upper/lower limit of pressure, O2 concentration, temperature and humidity and CO2 can be set. When exceeding certain value, the alarm will be automatically triggered. 

 · Pressure is automatically lowered when treatment is completed, alarm indicates the door can be opened and the animal can be taken out.

· Hand wheel tray to improve the safety of operators and avoid safety risks caused by operational errors .

· User-friendly design, fast and easy operation

· Treatment options can be customized, for example, O2 concentration, in-chamber pressure, and the duration of treatment.

· Real-time monitoring of O2 concentration, pressure, temperature, humidity, CO2 concentration, and atmospheric pressure in the chamber to ensure the safety of the treatment environment for animals in the chamber.

· The built-in oxygen production function of the instrument saves the need for external O2 cylinder supply. 

· High O2 flow rate reduces waiting time (Up to 20 l/min).

Applications

· Quickly correct the body's hypoxia state

· Improve microcirculation

· Prevention and treatment of all types of edema

· Promote the establishment of collateral circulation and increase the permeability of the blood-brain barrier

· Accelerate lesion repair

· Inhibition of bacteria and microorganisms

Configuration

NameModelDescriptions
Laboratory Animal Hyperbaric ChamberProOx-820Specifically designed for experimental animals 


Reference

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[2]Guijuan Chen,Kang Cheng,Yun Niu,Li Zhu,Xueting Wang.Epicatechin gallate prevents inflammatory response in hypoxia-activated microglia and cerebral edema by inhibiting NF-κB signaling.[J]Archives of Biochemistry and Biophysics ,Volume 729, 109393;


[3]Yapeng,LuPanpanChang,WangwangDing,JiangpeiBian,DanWang,XuetingWang,QianqianLuo,XiaomeiWu,LiZhu.Pharmacological inhibition of mitochondrial division attenuates simulated high-altitude exposure-induced cerebral edema in mice: Involvement of inhibition of the NF-κB signaling pathway in glial cells.[J] European Journal of Pharmacology,Volume 929,2022,175137


[4]Jun-Yu Wei, Miao-Yue Hu, Xiu-Qi Chen, Feng-Ying Lei, Jin-Shuang Wei, Jie Chen, Xuan-Kai Qin & Yuan-Han Qin .Rosiglitazone attenuates hypoxia-induced renal cell apoptosis by inhibiting NF-κB signaling pathway in a PPARγ-dependent manner, [J] European Journal of Pharmacology,Renal Failure, 44:1, 2056-2065


[5]Yilan Wang, Zherui Shen, Caixia Pei, Sijing Zhao, Nan Jia, Demei Huang, Xiaomin Wang, Yongcan Wu, Shihua Shi, Yacong He, Zhenxing Wang,Eleutheroside B ameliorated high altitude pulmonary edema by attenuating ferroptosis and necroptosis through Nrf2-antioxidant response signaling, [J] Biomedicine & Pharmacotherapy, Volume 156, 2022,113982



[6]Fang Zhao, Yan Meng, Yue Wang, Siqi Fan, Yu Liu,Xiangfeng Zhang, Chenyang Ran, Hongxin Wang and Meili Lu,Protective effect of Astragaloside IV on chronic intermittent hypoxia-induced vascular endothelial dysfunction through the calpain-1/SIRT1/AMPK signaling pathway.[J] Frontiers in Pharmacology,10.3389/fphar.2022.920977


[7]Jing Zhang , Jian-Zhong Jiang , Jun Xu , Chen-Yu Xu , Shan Mao , Ying Shi , Wei Gu , Chun-Fang Zou , Yue-Ming Zhao , Liang Ye.”Identification of Novel Biomarkers for Abdominal Aortic Aneurysm Promoted by Obstructive Sleep Apnea”[J]Annals of Vascular Surgery, Available online 2 February 2023

[8]Zhang, C., Sun, Y., Guo, Y. et al. “JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension. “[J].Cell Death Discov. 9, 98 (2023).


[9]Zhang, L., Liu, X., Wei, Q. et al. “Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p. “[J]. Mamm Genome 34, 76–89 (2023).